Riociguat prevents hyperoxia-induced lung injury and pulmonary hypertension in neonatal rats without effects on long bone growth

Bronchopulmonary dysplasia (BPD) remains the most common and serious chronic lung disease of premature infants. Severe BPD complicated with pulmonary hypertension (PH) increases the mortality of these infants. Riociguat is an allosteric soluble guanylate cyclase stimulator and is approved by the FDA...

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Publicado en:PLoS One
Autores principales: Donda, Keyur, Zambrano, Ronald, Moon, Younghye, Percival, Justin, Vaidya, Ruben, Dapaah-Siakwan, Fredrick, Luo, Shihua, Duncan, Matthew R., Bao, Yong, Wang, Luqing, Qin, Ling, Benny, Merline, Young, Karen, Wu, Shu
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038999/
https://ncbi.nlm.nih.gov/pubmed/29990355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0199927
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