Riociguat prevents hyperoxia-induced lung injury and pulmonary hypertension in neonatal rats without effects on long bone growth

Bronchopulmonary dysplasia (BPD) remains the most common and serious chronic lung disease of premature infants. Severe BPD complicated with pulmonary hypertension (PH) increases the mortality of these infants. Riociguat is an allosteric soluble guanylate cyclase stimulator and is approved by the FDA...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS One
Κύριοι συγγραφείς: Donda, Keyur, Zambrano, Ronald, Moon, Younghye, Percival, Justin, Vaidya, Ruben, Dapaah-Siakwan, Fredrick, Luo, Shihua, Duncan, Matthew R., Bao, Yong, Wang, Luqing, Qin, Ling, Benny, Merline, Young, Karen, Wu, Shu
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2018
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038999/
https://ncbi.nlm.nih.gov/pubmed/29990355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0199927
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