Self-nanomicellizing solid dispersion of edaravone: part I – oral bioavailability improvement

BACKGROUND: Edaravone (EDR) is known for its free radical scavenging, antiapoptotic, antinecrotic, and anticytokine effects in neurological and non-neurological diseases. It is currently available clinically as Radicava(®) and Radicut(®), intravenous medications, recently approved for the treatment...

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Vydáno v:Drug Des Devel Ther
Hlavní autoři: Parikh, Ankit, Kathawala, Krishna, Tan, Chun Chuan, Garg, Sanjay, Zhou, Xin-Fu
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2018
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038876/
https://ncbi.nlm.nih.gov/pubmed/30013324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S161940
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