Leishmanicidal and Immunomodulatory Activities of the Palladacycle Complex DPPE 1.1, a Potential Candidate for Treatment of Cutaneous Leishmaniasis

The present study focused on the activity of the palladacycle complex DPPE 1.1 on Leishmania (Leishmania) amazonensis. Promastigotes of L. (L.) amazonensis were destroyed in vitro by nanomolar concentrations of DPPE 1.1, whereas intracellular amastigotes were killed at drug concentrations fivefold l...

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Vydáno v:Front Microbiol
Hlavní autoři: dos Santos, Isabela B., da Silva, Danielle A. M., Paz, Fabiana A. C. R., Garcia, Daniel M., Carmona, Adriana K., Teixeira, Daniela, Longo-Maugéri, Ieda M., Katz, Simone, Barbiéri, Clara L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038773/
https://ncbi.nlm.nih.gov/pubmed/30018604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.01427
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