Leishmanicidal and Immunomodulatory Activities of the Palladacycle Complex DPPE 1.1, a Potential Candidate for Treatment of Cutaneous Leishmaniasis

The present study focused on the activity of the palladacycle complex DPPE 1.1 on Leishmania (Leishmania) amazonensis. Promastigotes of L. (L.) amazonensis were destroyed in vitro by nanomolar concentrations of DPPE 1.1, whereas intracellular amastigotes were killed at drug concentrations fivefold l...

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Publicat a:Front Microbiol
Autors principals: dos Santos, Isabela B., da Silva, Danielle A. M., Paz, Fabiana A. C. R., Garcia, Daniel M., Carmona, Adriana K., Teixeira, Daniela, Longo-Maugéri, Ieda M., Katz, Simone, Barbiéri, Clara L.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038773/
https://ncbi.nlm.nih.gov/pubmed/30018604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.01427
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