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The TGFβ-signaling pathway and colorectal cancer: associations between dysregulated genes and miRNAs

BACKGROUND: The TGFβ-signaling pathway plays an important role in the pathogenesis of colorectal cancer (CRC). Loss of function of several genes within this pathway, such as bone morphogenetic proteins (BMPs) have been seen as key events in CRC progression. METHODS: In this study we comprehensively...

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Publicado en:J Transl Med
Autores principales: Pellatt, Andrew J., Mullany, Lila E., Herrick, Jennifer S., Sakoda, Lori C., Wolff, Roger K., Samowitz, Wade S., Slattery, Martha L.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038278/
https://ncbi.nlm.nih.gov/pubmed/29986714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1566-8
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