The TGFβ-signaling pathway and colorectal cancer: associations between dysregulated genes and miRNAs

BACKGROUND: The TGFβ-signaling pathway plays an important role in the pathogenesis of colorectal cancer (CRC). Loss of function of several genes within this pathway, such as bone morphogenetic proteins (BMPs) have been seen as key events in CRC progression. METHODS: In this study we comprehensively...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Pellatt, Andrew J., Mullany, Lila E., Herrick, Jennifer S., Sakoda, Lori C., Wolff, Roger K., Samowitz, Wade S., Slattery, Martha L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038278/
https://ncbi.nlm.nih.gov/pubmed/29986714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1566-8
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