Genotype-guided versus traditional clinical dosing of warfarin in patients of Asian ancestry: a randomized controlled trial

BACKGROUND: Genotype-guided warfarin dosing has been shown in some randomized trials to improve anticoagulation outcomes in individuals of European ancestry, yet its utility in Asian patients remains unresolved. METHODS: An open-label, non-inferiority, 1:1 randomized trial was conducted at three aca...

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Detalhes bibliográficos
Publicado no:BMC Med
Main Authors: Syn, Nicholas L., Wong, Andrea Li-Ann, Lee, Soo-Chin, Teoh, Hock-Luen, Yip, James Wei Luen, Seet, Raymond CS, Yeo, Wee Tiong, Kristanto, William, Bee, Ping-Chong, Poon, LM, Marban, Patrick, Wu, Tuck Seng, Winther, Michael D., Brunham, Liam R., Soong, Richie, Tai, Bee-Choo, Goh, Boon-Cher
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038204/
https://ncbi.nlm.nih.gov/pubmed/29986700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-018-1093-8
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