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Local, Controlled Release In Vivo of Vascular Endothelial Growth Factor Within a Subcutaneous Scaffolded Islet Implant Reduces Early Islet Necrosis and Improves Performance of the Graft

Islet transplantation remains the only alternative to daily insulin therapy for control of type 1 diabetes (T1D) in humans. To avoid the drawbacks of intrahepatic islet transplantation, we are developing a scaffolded islet implant to transplant islets into nonhepatic sites. The implant test bed, siz...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Transplant
Hauptverfasser: Gebe, John A., Preisinger, Anton, Gooden, Michel D., D’Amico, Leonard A., Vernon, Robert B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038045/
https://ncbi.nlm.nih.gov/pubmed/29756517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0963689718754562
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