Reversal of Diabetes in Mice With a Bioengineered Islet Implant Incorporating a Type I Collagen Hydrogel and Sustained Release of Vascular Endothelial Growth Factor

We have developed a bioengineered implant (BI) to evaluate strategies to promote graft survival and function in models of islet transplantation in mice. The BI, sized for implantation within a fold of intestinal mesentery, consists of a disk-shaped, polyvinyl alcohol sponge infused with a type I col...

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Auteurs principaux: Vernon, Robert B., Preisinger, Anton, Gooden, Michel D., D’Amico, Leonard A., Yue, Betty B., Bollyky, Paul L., Kuhr, Christian S., Hefty, Thomas R., Nepom, Gerald T., Gebe, John A.
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829609/
https://ncbi.nlm.nih.gov/pubmed/23231959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096368912X636786
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