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Challenging the Drug-Likeness Dogma for New Drug Discovery in Tuberculosis

The emergence of multi- and extensively drug resistant tuberculosis worldwide poses a great threat to human health and highlight the need to discover and develop new, effective and inexpensive antituberculosis agents. High-throughput screening assays against well-validated drug targets and structure...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Machado, Diana, Girardini, Miriam, Viveiros, Miguel, Pieroni, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6037898/
https://ncbi.nlm.nih.gov/pubmed/30018597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.01367
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