Priming of dendritic cells by DNA-containing extracellular vesicles from activated T cells through antigen-driven contacts

Interaction of T cell with antigen-bearing dendritic cells (DC) results in T cell activation, but whether this interaction has physiological consequences on DC function is largely unexplored. Here we show that when antigen-bearing DCs contact T cells, DCs initiate anti-pathogenic programs. Signals o...

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Publicado en:Nat Commun
Main Authors: Torralba, Daniel, Baixauli, Francesc, Villarroya-Beltri, Carolina, Fernández-Delgado, Irene, Latorre-Pellicer, Ana, Acín-Pérez, Rebeca, Martín-Cófreces, Noa B, Jaso-Tamame, Ángel Luis, Iborra, Salvador, Jorge, Inmaculada, González-Aseguinolaza, Gloria, Garaude, Johan, Vicente-Manzanares, Miguel, Enríquez, José Antonio, Mittelbrunn, María, Sánchez-Madrid, Francisco
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6037695/
https://ncbi.nlm.nih.gov/pubmed/29985392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05077-9
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