Necrosis Driven Triglyceride Synthesis Primes Macrophages for Inflammation During Mycobacterium tuberculosis Infection

Pulmonary tuberculosis (TB) exhibits granulomatous inflammation, a site of controlling bacterial dissemination at the cost of host tissue damage. Intrigued by the granuloma type-dependent expression of inflammatory markers in TB, we sought to investigate underlying metabolic changes that drive ampli...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Jaisinghani, Neetika, Dawa, Stanzin, Singh, Kaurab, Nandy, Ananya, Menon, Dilip, Bhandari, Purva Deepak, Khare, Garima, Tyagi, Anil, Gandotra, Sheetal
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6037689/
https://ncbi.nlm.nih.gov/pubmed/30018616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01490
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