Adipocyte Model of Mycobacterium tuberculosis Infection Reveals Differential Availability of Iron to Bacilli in the Lipid-Rich Caseous Environment

Mycobacterium tuberculosis, a successful human pathogen, utilizes multiple carbon sources from the host but adapts to a fatty-acid-rich environment in vivo. We sought to delineate the physiologic response of M. tuberculosis to a lipid-rich environment by using differentiated adipocytes as a model sy...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Nandy, Ananya, Mondal, Anupam Kumar, Pandey, Rajesh, Arumugam, Prabhakar, Dawa, Stanzin, Jaisinghani, Neetika, Rao, Vivek, Dash, Debasis, Gandotra, Sheetal
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964510/
https://ncbi.nlm.nih.gov/pubmed/29632245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00041-18
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