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Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis
Alterations in microRNA (miRNA) processing have been previously linked to aging. Here we used the small molecule enoxacin to pharmacologically interfere with miRNA biogenesis and study how it affects aging in C. elegans. Enoxacin extended worm lifespan and promoted survival under normal and oxidativ...
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| Publicado no: | Redox Biol |
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| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6037660/ https://ncbi.nlm.nih.gov/pubmed/29986212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.06.006 |
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