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Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis
Alterations in microRNA (miRNA) processing have been previously linked to aging. Here we used the small molecule enoxacin to pharmacologically interfere with miRNA biogenesis and study how it affects aging in C. elegans. Enoxacin extended worm lifespan and promoted survival under normal and oxidativ...
Gorde:
| Argitaratua izan da: | Redox Biol |
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| Egile Nagusiak: | , , , , , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Elsevier
2018
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6037660/ https://ncbi.nlm.nih.gov/pubmed/29986212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.06.006 |
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