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Optimization of voriconazole therapy for the treatment of invasive fungal infections in adults

Therapeutic concentrations of voriconazole in invasive fungal infections (IFIs) are ensured using drug monitoring approach, which relies on attainment of steady state pharmacokinetics. For voriconazole, time to reach steady state can vary from 5–7 days, not optimal for critically ill patients. We de...

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Publicado en:Clin Pharmacol Ther
Main Authors: Mangal, Naveen, Hamadeh, Issam, Arwood, Meghan J., Cavallari, Larisa H., Samant, Tanay S., Klinker, Kenneth P., Bulitta, Jurgen, Schmidt, Stephan
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6037619/
https://ncbi.nlm.nih.gov/pubmed/29315506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1012
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