Extracellular Vesicles Derived from Hypoxic Human Mesenchymal Stem Cells Attenuate GSK3β Expression via miRNA-26a in an Ischemia-Reperfusion Injury Model

PURPOSE: Bioactive molecules critical to intracellular signaling are contained in extracellular vesicles (EVs) and have cardioprotective effects in ischemia/reperfusion (IR) injured hearts. This study investigated the mechanism of the cardioprotective effects of EVs derived from hypoxia-precondition...

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Detalhes bibliográficos
Publicado no:Yonsei Med J
Main Authors: Park, Hyewon, Park, Hyelim, Mun, Dasom, Kang, Jiyoung, Kim, Hyoeun, Kim, Michael, Cui, Shanyu, Lee, Seung-Hyun, Joung, Boyoung
Formato: Artigo
Idioma:Inglês
Publicado em: Yonsei University College of Medicine 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6037597/
https://ncbi.nlm.nih.gov/pubmed/29978610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3349/ymj.2018.59.6.736
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