Evolution of chemokine receptors is driven by mutations in the sodium binding site

Chemokines and their receptors (members of the GPCR super-family) are involved in a wide variety of physiological processes and diseases; thus, understanding the specificity of the chemokine receptor family could help develop new receptor specific drugs. Here, we explore the evolutionary mechanisms...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Comput Biol
Prif Awduron: Taddese, Bruck, Deniaud, Madeline, Garnier, Antoine, Tiss, Asma, Guissouma, Hajer, Abdi, Hervé, Henrion, Daniel, Chabbert, Marie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2018
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6037435/
https://ncbi.nlm.nih.gov/pubmed/29912865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006209
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