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Evolution of chemokine receptors is driven by mutations in the sodium binding site
Chemokines and their receptors (members of the GPCR super-family) are involved in a wide variety of physiological processes and diseases; thus, understanding the specificity of the chemokine receptor family could help develop new receptor specific drugs. Here, we explore the evolutionary mechanisms...
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| Publicado no: | PLoS Comput Biol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6037435/ https://ncbi.nlm.nih.gov/pubmed/29912865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006209 |
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