Urine lipoarabinomannan glycan in HIV-negative patients with pulmonary tuberculosis correlates with disease severity

An accurate urine test for pulmonary tuberculosis (TB), affecting 9.6 million patients worldwide, is critically needed for surveillance and treatment management. Past attempts failed to reliably detect the mycobacterial glycan antigen lipoarabinomannan (LAM), a marker of active TB, in HIV-negative,...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Transl Med
Autori principali: Paris, Luisa, Magni, Ruben, Zaidi, Fatima, Araujo, Robyn, Saini, Neal, Harpole, Michael, Coronel, Jorge, Kirwan, Daniela E., Steinberg, Hannah, Gilman, Robert H., Petricoin, Emanuel F., Nisini, Roberto, Luchini, Alessandra, Liotta, Lance
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for the Advancement of Science 2017
Soggetti:
Tuberculosis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6037412/
https://ncbi.nlm.nih.gov/pubmed/29237757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aal2807
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