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By blocking hexokinase-2 phosphorylation, limonin suppresses tumor glycolysis and induces cell apoptosis in hepatocellular carcinoma

INTRODUCTION: The purpose of present study was to investigate the effect of limonin on tumor glycolysis and the underlying mechanisms in hepatocellular carcinoma (HCC). METHODS: Cell proliferation and colony formation assays were performed to evaluate the potency of limonin against HCC cells in vitr...

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Pubblicato in:Onco Targets Ther
Autori principali: Yao, Junliang, Liu, Jingtian, Zhao, Wensheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6037266/
https://ncbi.nlm.nih.gov/pubmed/30013360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S165220
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