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Chrysin inhibited tumor glycolysis and induced apoptosis in hepatocellular carcinoma by targeting hexokinase-2

BACKGROUND: Hexokinase-2(HK-2) plays dual roles in glucose metabolism and mediation of cell apoptosis, making it an attractive target for cancer therapy. Chrysin is a natural flavone found in plant extracts which are widely used as herb medicine in China. In the present study, we investigated the an...

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Détails bibliographiques
Publié dans:J Exp Clin Cancer Res
Auteurs principaux: Xu, Dong, Jin, Junzhe, Yu, Hao, Zhao, Zheming, Ma, Dongyan, Zhang, Chundong, Jiang, Honglei
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359903/
https://ncbi.nlm.nih.gov/pubmed/28320429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0514-4
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