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Metal-free formal synthesis of phenoxazine

A transition metal-free formal synthesis of phenoxazine is presented. The key step of the sequence is a high-yielding O-arylation of a phenol with an unsymmetrical diaryliodonium salt to provide an ortho-disubstituted diaryl ether. This species was cyclized to acetylphenoxazine in moderate yield. Th...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Kervefors, Gabriella, Becker, Antonia, Dey, Chandan, Olofsson, Berit
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036965/
https://ncbi.nlm.nih.gov/pubmed/30013676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.14.126
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