Application of Isobaric Tags for Relative and Absolute Quantification (iTRAQ) Coupled with Two-Dimensional Liquid Chromatography/Tandem Mass Spectrometry in Quantitative Proteomic Analysis for Discovery of Serum Biomarkers for Idiopathic Pulmonary Fibrosis

BACKGROUND: The present study was performed to explore the presence of informative protein biomarkers of human serum proteome in idiopathic pulmonary fibrosis (IPF). MATERIAL/METHODS: Serum samples were profiled using iTRAQ coupled with two-dimensional liquid chromatography/tandem mass spectrometry...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Med Sci Monit
Hauptverfasser: Zhang, Ying, Xin, Qian, Wu, Zhen, Wang, Chaochao, Wang, Yongbin, Wu, Qian, Niu, Rui
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Scientific Literature, Inc. 2018
Schlagworte:
Lab/In Vitro Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036962/
https://ncbi.nlm.nih.gov/pubmed/29909421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.908702
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