Tissue-resident memory features are linked to the magnitude of cytotoxic T cell responses in human lung cancer

Therapies that boost the anti-tumor responses of cytotoxic T lymphocytes (CTLs) have shown promise; however, clinical responses to the immunotherapeutic agents currently available vary considerably, and the molecular basis of this is unclear. We performed transcriptomic profiling of tumor-infiltrati...

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Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Ganesan, Anusha-Preethi, Clarke, James, Wood, Oliver, Garrido-Martin, Eva M, Chee, Serena J, Mellows, Toby, Samaniego-Castruita, Daniela, Singh, Divya, Seumois, Grégory, Alzetani, Aiman, Woo, Edwin, Friedmann, Peter S, King, Emma V, Thomas, Gareth J, Sanchez-Elsner, Tilman, Vijayanand, Pandurangan, Ottensmeier, Christian H
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036910/
https://ncbi.nlm.nih.gov/pubmed/28628092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3775
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