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PDE4a predicts poor prognosis and promotes metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma

Phosphodiesterases (PDEs) was found to be involved in a variety of cancer pathologies by modulating the degradation of levels of cAMP/cGMP. However, the prognostic significance and biological effect of PDE4a in hepatocellular carcinoma (HCC) have not been understood completely. In the present study,...

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Detalhes bibliográficos
Publicado no:J Cancer
Main Authors: Peng, Yanghong, Li, Yijun, Tian, Yu, Ao, Guokun
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036708/
https://ncbi.nlm.nih.gov/pubmed/30026835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.24079
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