Proteinase-activated receptor 2 promotes tumor cell proliferation and metastasis by inducing epithelial-mesenchymal transition and predicts poor prognosis in hepatocellular carcinoma

AIM: To clarify the role of proteinase-activated receptor 2 (PAR2) in hepatocellular carcinoma, especially in the process of metastasis. METHODS: PAR2 expression levels were assessed by qRT-PCR and immunohistochemistry (IHC) in patient tissues and in hepatocellular carcinoma cell lines SMMC-7721 and...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Sun, Liang, Li, Pi-Bao, Yao, Yan-Fen, Xiu, Ai-Yuan, Peng, Zhi, Bai, Yu-Huan, Gao, Yan-Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2018
Assuntos:
Basic Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850131/
https://ncbi.nlm.nih.gov/pubmed/29563756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v24.i10.1120
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