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Epigenetic regulation of ID4 in the determination of the BRCAness phenotype in breast cancer
BRCAness breast tumors represent a group of sporadic tumors characterized by a reduction in BRCA1 gene expression. As BRCA1 is involved in double-strand breaks (DSBs) repair, dysfunctional BRCA pathway could make a tumor sensitive to DNA damaging drugs (e.g., platinum agents). Thus, accurately ident...
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| Publicado no: | Breast Cancer Res Treat |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6036618/ https://ncbi.nlm.nih.gov/pubmed/26610810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-015-3648-0 |
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