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Inhibition of RAGE Attenuates Cigarette Smoke-Induced Lung Epithelial Cell Damage via RAGE-Mediated Nrf2/DAMP Signaling

The oxidative stress and cellular apoptosis by environmental factor including cigarette smoke induces alveolar airway remodeling leading to chronic obstructive pulmonary disease (COPD). Recently, the receptor for advanced glycan end products (RAGE) which is highly expressed in alveolar epithelium is...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Lee, Hanbyeol, Lee, Jooyeon, Hong, Seok-Ho, Rahman, Irfan, Yang, Se-Ran
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036614/
https://ncbi.nlm.nih.gov/pubmed/30013476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00684
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