Overexpression of MTH1 and OGG1 proteins in ulcerative colitis-associated carcinogenesis

Oxidative stress, demonstrated by an accumulation of 8-hydroxy-2′-deoxyguanosine (8-OHdG), results in DNA damage, which is normally repaired by base excision repair enzymes including 8-OHdG DNA glycosylase (OGG1) and human MutY homolog (MUTYH), in addition to nucleotide pool sanitizing enzymes inclu...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Kumagae, Yoshiteru, Hirahashi, Minako, Takizawa, Katsumi, Yamamoto, Hidetaka, Gushima, Masaki, Esaki, Motohiro, Matsumoto, Takayuki, Nakamura, Masafumi, Kitazono, Takanari, Oda, Yoshinao
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036322/
https://ncbi.nlm.nih.gov/pubmed/30008864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.8812
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