The IGF2/IGF1R/Nanog Signaling Pathway Regulates the Proliferation of Acute Myeloid Leukemia Stem Cells

Acute myeloid leukemia is an aggressive disease characterized by clonal proliferation and differentiation into immature hematopoietic cells of dysfunctional myeloid precursors. Accumulating evidence shows that CD34(+)CD38(-) leukemia stem cells (LSCs) are responsible for drug resistance, metastasis,...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Xu, Dan-dan, Wang, Ying, Zhou, Peng-jun, Qin, Shu-rong, Zhang, Rong, Zhang, Yi, Xue, Xue, Wang, Jianping, Wang, Xia, Chen, Hong-ce, Wang, Xiao, Pan, Yu-wei, Zhang, Li, Yan, Hai-zhao, Liu, Qiu-ying, Liu, Zhong, Chen, Su-hong, Chen, Hong-yuan, Wang, Yi-fei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036281/
https://ncbi.nlm.nih.gov/pubmed/30013477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00687
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