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The IGF2/IGF1R/Nanog Signaling Pathway Regulates the Proliferation of Acute Myeloid Leukemia Stem Cells

Acute myeloid leukemia is an aggressive disease characterized by clonal proliferation and differentiation into immature hematopoietic cells of dysfunctional myeloid precursors. Accumulating evidence shows that CD34(+)CD38(-) leukemia stem cells (LSCs) are responsible for drug resistance, metastasis,...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Xu, Dan-dan, Wang, Ying, Zhou, Peng-jun, Qin, Shu-rong, Zhang, Rong, Zhang, Yi, Xue, Xue, Wang, Jianping, Wang, Xia, Chen, Hong-ce, Wang, Xiao, Pan, Yu-wei, Zhang, Li, Yan, Hai-zhao, Liu, Qiu-ying, Liu, Zhong, Chen, Su-hong, Chen, Hong-yuan, Wang, Yi-fei
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036281/
https://ncbi.nlm.nih.gov/pubmed/30013477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00687
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