Granulocyte-Colony Stimulating Factor-Overexpressing Mesenchymal Stem Cells Exhibit Enhanced Immunomodulatory Actions Through the Recruitment of Suppressor Cells in Experimental Chagas Disease Cardiomyopathy

Genetic modification of mesenchymal stem cells (MSCs) is a promising strategy to improve their therapeutic effects. Granulocyte-colony stimulating factor (G-CSF) is a growth factor widely used in the clinical practice with known regenerative and immunomodulatory actions, including the mobilization o...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Silva, Daniela N., Souza, Bruno S. F., Vasconcelos, Juliana F., Azevedo, Carine M., Valim, Clarissa X. R., Paredes, Bruno D., Rocha, Vinicius P. C., Carvalho, Gisele B., Daltro, Pamela S., Macambira, Simone G., Nonaka, Carolina K. V., Ribeiro-dos-Santos, Ricardo, Soares, Milena B. P.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036245/
https://ncbi.nlm.nih.gov/pubmed/30013550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01449
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