Age-Related Impaired Efficacy of Bone Marrow Cell Therapy for Myocardial Infarction Reflects a Decrease in B Lymphocytes

Treatment of myocardial infarction (MI) with bone marrow cells (BMCs) improves post-MI cardiac function in rodents. However, clinical trials of BMC therapy have been less effective. While most rodent experiments use young healthy donors, patients undergoing autologous cell therapy are older and post...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: An, Songtao, Wang, Xiaoyin, Ruck, Melissa A., Rodriguez, Hilda J., Kostyushev, Dmitry S., Varga, Monika, Luu, Emmy, Derakhshandeh, Ronak, Suchkov, Sergey V., Kogan, Scott C., Hermiston, Michelle L., Springer, Matthew L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036225/
https://ncbi.nlm.nih.gov/pubmed/29914756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.05.015
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