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Posttranslational Modifications of RAS Proteins

The three human RAS genes encode four proteins that play central roles in oncogenesis by acting as binary molecular switches that regulate signaling pathways for growth and differentiation. Each is subject to a set of posttranslational modifications (PTMs) that modify their activity or are required...

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Pubblicato in:Cold Spring Harb Perspect Med
Autori principali: Ahearn, Ian, Zhou, Mo, Philips, Mark R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035883/
https://ncbi.nlm.nih.gov/pubmed/29311131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a031484
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