Quercetin inhibits glucose transport by binding to an exofacial site on GLUT1

Quercetin, a common dietary flavone, is a competitive inhibitor of glucose uptake and is also thought to be transported into cells by GLUT1. In this study, we confirm that quercetin is a competitive inhibitor of GLUT1 and also demonstrate that newly synthesized compounds, WZB-117 and BAY-876 are rob...

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Détails bibliographiques
Publié dans:Biochimie
Auteurs principaux: Hamilton, Kathryn E., Rekman, Janelle F., Gunnink, Leesha K., Busscher, Brianna M., Scott, Jordan L., Tidball, Andrew M., Stehouwer, Nathan R., Johnecheck, Grace N., Looyenga, Brendan D., Louters, Larry L.
Format: Artigo
Langue:Inglês
Publié: 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035882/
https://ncbi.nlm.nih.gov/pubmed/29857184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2018.05.012
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