Can Microsatellite Status of Colorectal Cancer be Reliably Assessed after Neoadjuvant Therapy?

PURPOSE: Determination of microsatellite instability (MSI) by PCR is the gold standard; however, immunohistochemistry (IHC) of mismatch repair (MMR) proteins is frequently performed instead. The reliability of these methods on post-neoadjuvant-therapy specimens is unknown. We examined the effect of...

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Опубликовано в: :Clin Cancer Res
Главные авторы: Goldstein, Jennifer, Wu, William, Borras, Ester, Masand, Gita, Cuddy, Amanda, Mork, Maureen E., Bannon, Sarah A., Lynch, Patrick M., Rodriguez-Bigas, Miguel A., Taggart, Melissa W., Wu, Ji Y., Scheet, Paul, Kopetz, E. Scott, You, Y. Nancy, Vilar, Eduardo
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035875/
https://ncbi.nlm.nih.gov/pubmed/28522602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-2994
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