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Full control of ligand positioning reveals spatial thresholds for T cell receptor triggering
Elucidating the rules for receptor triggering in cell-cell and cell-matrix contacts requires precise control of ligand positioning in three dimensions. Here, we use the T cell receptor (TCR) as a model and subject T cells to different geometric arrangements of ligands, using a nanofabricated single-...
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| 發表在: | Nat Nanotechnol |
|---|---|
| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6035778/ https://ncbi.nlm.nih.gov/pubmed/29713075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41565-018-0113-3 |
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