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A critical role of IL-18 in transformation and maturation of naïve eosinophils to pathogenic eosinophils
The current studies demonstrate a critical role of IL-18 in transforming IL-5 generated naïve eosinophils into the distinct inflammatory CD101(+)CD274(+) expressing mature and activated tissue eosinophils that promote disease pathogenesis.
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| 出版年: | J Allergy Clin Immunol |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6035772/ https://ncbi.nlm.nih.gov/pubmed/29499224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2018.02.011 |
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