A critical role of IL-18 in transformation and maturation of naïve eosinophils to pathogenic eosinophils

The current studies demonstrate a critical role of IL-18 in transforming IL-5 generated naïve eosinophils into the distinct inflammatory CD101(+)CD274(+) expressing mature and activated tissue eosinophils that promote disease pathogenesis.

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Venkateshaiah, Sathisha Upparahalli, Mishra, Akanksha, Manohar, Murli, Verma, Alok K., Rajavelu, Priya, Niranjan, Rituraj, Wild, Laurianne G, Parada, Nereida A., Blecker, Uwe, Lasky, Joseph A., Mishra, Anil
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035772/
https://ncbi.nlm.nih.gov/pubmed/29499224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2018.02.011
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