Macrodiscs Comprising SMALPs for Oriented Sample Solid-State NMR Spectroscopy of Membrane Proteins

Macrodiscs, which are magnetically alignable lipid bilayer discs with diameters of >30 nm, were obtained by solubilizing protein-containing liposomes with styrene-maleic acid copolymers. Macrodiscs provide a detergent-free phospholipid bilayer environment for biophysical and functional studies of...

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Vydáno v:Biophys J
Hlavní autoři: Radoicic, Jasmina, Park, Sang Ho, Opella, Stanley J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2018
Témata:
Biophysical Letters
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035293/
https://ncbi.nlm.nih.gov/pubmed/29914645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.05.024
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