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Nanodiscs vs. Macrodiscs for NMR of Membrane Proteins

It is challenging to find membrane mimics that stabilize the native structure, dynamics, and functions of membrane proteins. In a recent advance, nanodiscs have been shown to provide a bilayer environment compatible with solution NMR. Increasing the lipid to “belt” peptide ratio expands their diamet...

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Detalhes bibliográficos
Main Authors: Park, Sang Ho, Berkamp, Sabrina, Cook, Gabriel A., Chan, Michelle K., Viadiu, Hector, Opella, Stanley J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236031/
https://ncbi.nlm.nih.gov/pubmed/21936505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201289c
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