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miR-103 promotes endothelial maladaptation by targeting lncWDR59

Blood flow at arterial bifurcations and curvatures is naturally disturbed. Endothelial cells (ECs) fail to adapt to disturbed flow, which transcriptionally direct ECs toward a maladapted phenotype, characterized by chronic regeneration of injured ECs. MicroRNAs (miRNAs) can regulate EC maladaptation...

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Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Natarelli, Lucia, Geißler, Claudia, Csaba, Gergely, Wei, Yuanyuan, Zhu, Mengyu, di Francesco, Andrea, Hartmann, Petra, Zimmer, Ralf, Schober, Andreas
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035258/
https://ncbi.nlm.nih.gov/pubmed/29980665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05065-z
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