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Polymorphisms and haplotypes in the promoter of the TNF-α gene are associated with disease severity of severe fever with thrombocytopenia syndrome in Chinese Han population

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease that is caused by a novel bunyavirus, SFTSV. We assessed whether the single nucleotide polymorphisms (SNPs) in the tumor necrosis factor-alpha (TNF-α) were associated with risk to severity of SFTS. Five TNF-α SNPs (...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS Negl Trop Dis
Main Authors: Xing, Bo, Li, Xiao-Kun, Zhang, Shao-Fei, Lu, Qing-Bin, Du, Juan, Zhang, Pan-He, Yang, Zhen-Dong, Cui, Ning, Guo, Chen-Tao, Cao, Wu-Chun, Zhang, Xiao-Ai, Liu, Wei
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6034906/
https://ncbi.nlm.nih.gov/pubmed/29939989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006547
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