Polymorphisms and haplotypes in the promoter of the TNF-α gene are associated with disease severity of severe fever with thrombocytopenia syndrome in Chinese Han population

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease that is caused by a novel bunyavirus, SFTSV. We assessed whether the single nucleotide polymorphisms (SNPs) in the tumor necrosis factor-alpha (TNF-α) were associated with risk to severity of SFTS. Five TNF-α SNPs (...

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Dettagli Bibliografici
Pubblicato in:PLoS Negl Trop Dis
Autori principali: Xing, Bo, Li, Xiao-Kun, Zhang, Shao-Fei, Lu, Qing-Bin, Du, Juan, Zhang, Pan-He, Yang, Zhen-Dong, Cui, Ning, Guo, Chen-Tao, Cao, Wu-Chun, Zhang, Xiao-Ai, Liu, Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6034906/
https://ncbi.nlm.nih.gov/pubmed/29939989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006547
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