Polymorphisms and haplotypes in the promoter of the TNF-α gene are associated with disease severity of severe fever with thrombocytopenia syndrome in Chinese Han population

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease that is caused by a novel bunyavirus, SFTSV. We assessed whether the single nucleotide polymorphisms (SNPs) in the tumor necrosis factor-alpha (TNF-α) were associated with risk to severity of SFTS. Five TNF-α SNPs (...

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Dades bibliogràfiques
Publicat a:PLoS Negl Trop Dis
Autors principals: Xing, Bo, Li, Xiao-Kun, Zhang, Shao-Fei, Lu, Qing-Bin, Du, Juan, Zhang, Pan-He, Yang, Zhen-Dong, Cui, Ning, Guo, Chen-Tao, Cao, Wu-Chun, Zhang, Xiao-Ai, Liu, Wei
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6034906/
https://ncbi.nlm.nih.gov/pubmed/29939989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006547
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