Polymorphisms and haplotypes in the promoter of the TNF-α gene are associated with disease severity of severe fever with thrombocytopenia syndrome in Chinese Han population

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease that is caused by a novel bunyavirus, SFTSV. We assessed whether the single nucleotide polymorphisms (SNPs) in the tumor necrosis factor-alpha (TNF-α) were associated with risk to severity of SFTS. Five TNF-α SNPs (...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Xing, Bo, Li, Xiao-Kun, Zhang, Shao-Fei, Lu, Qing-Bin, Du, Juan, Zhang, Pan-He, Yang, Zhen-Dong, Cui, Ning, Guo, Chen-Tao, Cao, Wu-Chun, Zhang, Xiao-Ai, Liu, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6034906/
https://ncbi.nlm.nih.gov/pubmed/29939989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006547
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