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Pharmacogenetic manipulation of the nucleus accumbens alters binge-like alcohol drinking in mice

BACKGROUND: Chronic alcohol intake leads to long lasting changes in reward- and stress-related neuronal circuitry. The nucleus accumbens (NAc) is an integral component of this circuitry. Here, we investigate the effects of DREADDs (Designer Receptors Exclusively Activated by Designer Drugs) on neuro...

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Publicado en:Alcohol Clin Exp Res
Main Authors: Purohit, Kush, Parekh, Puja K., Kern, Joseph, Logan, Ryan W., Liu, Zheng, Huang, Yanhua, McClung, Colleen A., Crabbe, John C., Ozburn, Angela R.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6034712/
https://ncbi.nlm.nih.gov/pubmed/29668112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.13626
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