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Matrix metalloproteinase-9 mediates the deleterious effects of α2-antiplasmin on blood brain barrier breakdown and ischemic brain injury in experimental stroke
During acute brain ischemia, α2-antiplasmin markedly enhances brain injury, blood brain barrier breakdown and matrix metalloproteinase-9 (MMP-9) expression. Although α2-antiplasmin inhibits fibrin thrombus-degradation, and MMP-9 is a collagen-degrading enzyme altering blood brain barrier, both have...
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| Publicado no: | Neuroscience |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6034708/ https://ncbi.nlm.nih.gov/pubmed/29294343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2017.12.021 |
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