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Broadly Neutralizing Antibodies to HIV and Their Role in Vaccine Design

HIV employs multiple means to evade the humoral immune response, particularly the elicitation of and recognition by broadly neutralizing antibodies (bnAbs). Such antibodies can act antivirally against a wide spectrum of viruses by targeting relatively conserved regions on the surface HIV envelope tr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Annu Rev Immunol
Hauptverfasser: Burton, Dennis R., Hangartner, Lars
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6034635/
https://ncbi.nlm.nih.gov/pubmed/27168247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-immunol-041015-055515
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