A Recombinant Baculovirus Efficiently Generates Recombinant Adeno-Associated Virus Vectors in Cultured Insect Cells and Larvae

Current large-scale recombinant adeno-associated virus (rAAV) production systems based on the baculovirus expression vector (BEV) remain complicated and cost-intensive, and they lack versatility and flexibility. Here we present a novel recombinant baculovirus integrated with all packaging elements f...

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Publicado en:Mol Ther Methods Clin Dev
Autores principales: Wu, Yang, Jiang, Liangyu, Geng, Hao, Yang, Tian, Han, Zengpeng, He, Xiaobing, Lin, Kunzhang, Xu, Fuqiang
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Gene & Cell Therapy 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6034586/
https://ncbi.nlm.nih.gov/pubmed/29988889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2018.05.005
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