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AftD functions as an α1 → 5 arabinofuranosyltransferase involved in the biosynthesis of the mycobacterial cell wall core

Arabinogalactan (AG) is an essential structural macromolecule present in the cell wall of Mycobacterium tuberculosis, serving to connect peptidoglycan with the outer mycolic acid layer. The D-arabinan segment is a highly branched component of AG and is assembled in a step-wise fashion by a variety o...

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Détails bibliographiques
Publié dans:Cell Surf
Auteurs principaux: Alderwick, Luke J., Birch, Helen L., Krumbach, Karin, Bott, Michael, Eggeling, Lothar, Besra, Gurdyal S.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6034362/
https://ncbi.nlm.nih.gov/pubmed/29998212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcsw.2017.10.001
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